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/Advantages of the combined use of "Amoxicillin + Enrofloxacin"

Enrofloxacin is an animal-specific synthetic fluoroquinolone antibacterial drug. It has a strong bactericidal effect on gram-positive bacteria, gram-negative bacteria and mycoplasma. Its anti-mycoplasma activity is stronger than that of macrolides and belongs to reproduction. A quick-acting bactericidal drug.

At present, the common dosage forms on the veterinary drug market are enrofloxacin injection and enrofloxacin soluble powder. Enrofloxacin injection is an essential medicine for pig farms, and enrofloxacin soluble powder has a bitter taste and poor palatability for pigs. It is not suitable for pigs to take orally. It has not been widely used in pigs for many years. In the past two years, in order to adapt to the palatability of pigs, manufacturers have carried out microencapsulation coating to cover up its original bitter taste and increase the palatability of pigs. In addition, enrofloxacin has a broad-spectrum bactericidal effect. , Has a good effect on the respiratory tract and intestinal infections of livestock and poultry. It has been widely used in pig raising gradually and achieved good results.

Amoxicillin belongs to the β-lactam penicillin broad-spectrum antibiotic. It has a bactericidal effect on both Gram-positive and Gram-negative bacteria. It is a quick-acting bactericidal drug during the reproductive period, and has a good effect on lung infections in livestock and poultry.

At present, the common dosage forms on the veterinary drug market are amoxicillin soluble powder and amoxicillin sodium for injection. Because of its rapid bactericidal effect and low toxicity and side effects, it is widely used in livestock and poultry. It is especially suitable for the daily health care of sows during pregnancy. It has a good effect on the respiratory and intestinal infections of pigs, especially for streptococcus and sows. Postpartum infection has a unique effect.

According to the principle of the combination of antimicrobial drugs in pharmacology, enrofloxacin and amoxicillin are both quick-acting bactericidal drugs during the reproductive period, and the combination of the two has a synergistic effect; according to the physical and chemical properties of the two in pharmacy, they are different There are different combinations of dosage forms. The specific product compatibility is as follows.

1. Enrofloxacin soluble powder (coating) + amoxicillin soluble powder, according to the different specifications ratio of the two, mixed materials, synergistic effect, suitable for all stages of the pig farm (piglet, fattening pig, sow, Breeding pigs) pigs (except sows during pregnancy, because enrofloxacin has toxic and side effects on embryos) daily health care, once a month, prevent the occurrence of various bacterial respiratory diseases and intestinal diseases in pig farms, and reduce the incidence of related diseases , Improve the economic efficiency of the pig farm.

2. Enrofloxacin injection (national standard) + amoxicillin sodium for injection, dilute amoxicillin sodium for injection with enrofloxacin injection, mixed intramuscular injection, synergistic effect, suitable for pigs caused by unknown causes Symptoms such as lameness, joint swelling, joint pain, claudication, unstable standing and other symptoms, such as related symptoms caused by Haemophilus parasuis disease and arthritis streptococcus.

Due to the long-term use of florfenicol, doxycycline hydrochloride, tilmicosin, tylosin and other drugs in pig farms for many years, many pig farms have developed severe drug resistance to them. Health care medicines are less sensitive to bacteria. Due to the low price of enrofloxacin and amoxicillin preparations, good effects and economical benefits, the bold choice of enrofloxacin and amoxicillin preparations is an ideal combination as a daily health care drug for pigs and the treatment of related diseases. select.

Respect for science, rational use of medicines, and improved efficiency are the first principles that pig farms follow.